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Quality of life patient-reported outcomes for locally advanced cutaneous melanoma

Locally advanced cutaneous melanoma has marked quality-of-life implications; however, the patient experience of symptom management and subsequent impact on quality of life has not been well described. This study aims to address the impact on patients of advanced cutaneous melanoma through qualitativ...

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Autores principales: Weitman, Evan S., Perez, Matthew, Thompson, John F., Andtbacka, Robert H. I., Dalton, Jo, Martin, Mona L., Miller, Talia, Gwaltney, Chad, Sarson, David, Wachter, Eric, Zager, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844587/
https://www.ncbi.nlm.nih.gov/pubmed/29261570
http://dx.doi.org/10.1097/CMR.0000000000000425
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author Weitman, Evan S.
Perez, Matthew
Thompson, John F.
Andtbacka, Robert H. I.
Dalton, Jo
Martin, Mona L.
Miller, Talia
Gwaltney, Chad
Sarson, David
Wachter, Eric
Zager, Jonathan S.
author_facet Weitman, Evan S.
Perez, Matthew
Thompson, John F.
Andtbacka, Robert H. I.
Dalton, Jo
Martin, Mona L.
Miller, Talia
Gwaltney, Chad
Sarson, David
Wachter, Eric
Zager, Jonathan S.
author_sort Weitman, Evan S.
collection PubMed
description Locally advanced cutaneous melanoma has marked quality-of-life implications; however, the patient experience of symptom management and subsequent impact on quality of life has not been well described. This study aims to address the impact on patients of advanced cutaneous melanoma through qualitative interviews. Adults with stage IIIB, IIIC, or IV (M1a) cutaneous melanoma were recruited from two cancer centers in the USA and one in Australia. Telephone interviews were conducted to assess how locoregionally advanced cutaneous melanoma impacted everyday life. Interviews were recorded, transcribed, and coded for qualitative analysis. Twenty-two melanoma patients were interviewed, mean age 69.7 years (range: 52–83), 64% male. The study included stage IIIB (36%), stage IIIC (59%), and stage IV M1a (5%) patients. Emotional health/self-perception issues were the most commonly identified (41% of patient impact expressions), including worry, concern, embarrassment, self-consciousness, fear, and thoughts of death. Limitations of lifestyle and activities were also identified (28% of expressions) including leisure and social activities, physical functioning, general functioning, and personal care. Coping strategies such as modified clothing choices, increased use of pain and/or anti-inflammatory medications, and avoidance/protection from the sun represented 20% of all impact expressions. Ratings of the degree of difficulty patients experienced (using an 11-point numerical rating scale) ranged from 0.0 to 10.0 (mean 5.7, SD 2.9). Condition-related and treatment-related factors were well characterized in patients with locally advanced cutaneous melanoma. This provides a strong foundation for assessment of how cutaneous melanoma impacts quality of life.
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spelling pubmed-58445872018-03-20 Quality of life patient-reported outcomes for locally advanced cutaneous melanoma Weitman, Evan S. Perez, Matthew Thompson, John F. Andtbacka, Robert H. I. Dalton, Jo Martin, Mona L. Miller, Talia Gwaltney, Chad Sarson, David Wachter, Eric Zager, Jonathan S. Melanoma Res ORIGINAL ARTICLES: Epidemiology Locally advanced cutaneous melanoma has marked quality-of-life implications; however, the patient experience of symptom management and subsequent impact on quality of life has not been well described. This study aims to address the impact on patients of advanced cutaneous melanoma through qualitative interviews. Adults with stage IIIB, IIIC, or IV (M1a) cutaneous melanoma were recruited from two cancer centers in the USA and one in Australia. Telephone interviews were conducted to assess how locoregionally advanced cutaneous melanoma impacted everyday life. Interviews were recorded, transcribed, and coded for qualitative analysis. Twenty-two melanoma patients were interviewed, mean age 69.7 years (range: 52–83), 64% male. The study included stage IIIB (36%), stage IIIC (59%), and stage IV M1a (5%) patients. Emotional health/self-perception issues were the most commonly identified (41% of patient impact expressions), including worry, concern, embarrassment, self-consciousness, fear, and thoughts of death. Limitations of lifestyle and activities were also identified (28% of expressions) including leisure and social activities, physical functioning, general functioning, and personal care. Coping strategies such as modified clothing choices, increased use of pain and/or anti-inflammatory medications, and avoidance/protection from the sun represented 20% of all impact expressions. Ratings of the degree of difficulty patients experienced (using an 11-point numerical rating scale) ranged from 0.0 to 10.0 (mean 5.7, SD 2.9). Condition-related and treatment-related factors were well characterized in patients with locally advanced cutaneous melanoma. This provides a strong foundation for assessment of how cutaneous melanoma impacts quality of life. Lippincott Williams & Wilkins 2018-04 2017-12-20 /pmc/articles/PMC5844587/ /pubmed/29261570 http://dx.doi.org/10.1097/CMR.0000000000000425 Text en Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle ORIGINAL ARTICLES: Epidemiology
Weitman, Evan S.
Perez, Matthew
Thompson, John F.
Andtbacka, Robert H. I.
Dalton, Jo
Martin, Mona L.
Miller, Talia
Gwaltney, Chad
Sarson, David
Wachter, Eric
Zager, Jonathan S.
Quality of life patient-reported outcomes for locally advanced cutaneous melanoma
title Quality of life patient-reported outcomes for locally advanced cutaneous melanoma
title_full Quality of life patient-reported outcomes for locally advanced cutaneous melanoma
title_fullStr Quality of life patient-reported outcomes for locally advanced cutaneous melanoma
title_full_unstemmed Quality of life patient-reported outcomes for locally advanced cutaneous melanoma
title_short Quality of life patient-reported outcomes for locally advanced cutaneous melanoma
title_sort quality of life patient-reported outcomes for locally advanced cutaneous melanoma
topic ORIGINAL ARTICLES: Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844587/
https://www.ncbi.nlm.nih.gov/pubmed/29261570
http://dx.doi.org/10.1097/CMR.0000000000000425
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