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Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry

Dose calculation for small field radiotherapy with heterogeneity often involves discrepancies, so that algorithms used by treatment planning systems (TPS) should be evaluated with reference to achieving optimal treatment results. Accuracy of two model based algorithms, AcurosXB (AcXB) and the analyt...

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Autores principales: Alagar, Ananda Giri Babu, Ganesh, Kadirampatti Mani, Kaviarasu, Karunakaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844627/
https://www.ncbi.nlm.nih.gov/pubmed/29374410
http://dx.doi.org/10.22034/APJCP.2018.19.1.253
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author Alagar, Ananda Giri Babu
Ganesh, Kadirampatti Mani
Kaviarasu, Karunakaran
author_facet Alagar, Ananda Giri Babu
Ganesh, Kadirampatti Mani
Kaviarasu, Karunakaran
author_sort Alagar, Ananda Giri Babu
collection PubMed
description Dose calculation for small field radiotherapy with heterogeneity often involves discrepancies, so that algorithms used by treatment planning systems (TPS) should be evaluated with reference to achieving optimal treatment results. Accuracy of two model based algorithms, AcurosXB (AcXB) and the analytical anisotropic algorithm (AAA) from Eclipse TPS, were here tested. Measurements are made using Gafchromic EBT3 films with indigenously generated lung phantoms irradiated with 6 MV photons. Lung phantoms contained two types of tumor plugs, one kept at an interface attached to the chest wall in right lung (RIT) and the other at the centre of the left lung (LCT). RIT and LCT were studied with two different tumor diameters, 1.5 cm and 2.5 cm. Scanned images were planned in TPS with 3D-CRT, IMRT and VMAT and individual plans for each tumor were irradiated keeping the Gafchromic film at the centre of the tumor to evaluate the dose distribution in the central plane. Both algorithms, irrespective of delivery techniques, showed more deviation with smaller than larger diameter tumors. Also, both demonstrated maximum deviation at the junction of tumor and lung in both RIT and LCT cases. However, the deviation observed was higher with AAA and a minimal acceptable deviation of within 4 % was achieved with AcurosXB.
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spelling pubmed-58446272018-03-20 Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry Alagar, Ananda Giri Babu Ganesh, Kadirampatti Mani Kaviarasu, Karunakaran Asian Pac J Cancer Prev Research Article Dose calculation for small field radiotherapy with heterogeneity often involves discrepancies, so that algorithms used by treatment planning systems (TPS) should be evaluated with reference to achieving optimal treatment results. Accuracy of two model based algorithms, AcurosXB (AcXB) and the analytical anisotropic algorithm (AAA) from Eclipse TPS, were here tested. Measurements are made using Gafchromic EBT3 films with indigenously generated lung phantoms irradiated with 6 MV photons. Lung phantoms contained two types of tumor plugs, one kept at an interface attached to the chest wall in right lung (RIT) and the other at the centre of the left lung (LCT). RIT and LCT were studied with two different tumor diameters, 1.5 cm and 2.5 cm. Scanned images were planned in TPS with 3D-CRT, IMRT and VMAT and individual plans for each tumor were irradiated keeping the Gafchromic film at the centre of the tumor to evaluate the dose distribution in the central plane. Both algorithms, irrespective of delivery techniques, showed more deviation with smaller than larger diameter tumors. Also, both demonstrated maximum deviation at the junction of tumor and lung in both RIT and LCT cases. However, the deviation observed was higher with AAA and a minimal acceptable deviation of within 4 % was achieved with AcurosXB. West Asia Organization for Cancer Prevention 2018 /pmc/articles/PMC5844627/ /pubmed/29374410 http://dx.doi.org/10.22034/APJCP.2018.19.1.253 Text en Copyright: © Asian Pacific Journal of Cancer Prevention http://creativecommons.org/licenses/BY-SA/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Research Article
Alagar, Ananda Giri Babu
Ganesh, Kadirampatti Mani
Kaviarasu, Karunakaran
Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry
title Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry
title_full Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry
title_fullStr Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry
title_full_unstemmed Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry
title_short Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry
title_sort dose calculation accuracy of aaa and acurosxb algorithms for small central and interface lung lesions - verification with gafchromic film dosimetry
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844627/
https://www.ncbi.nlm.nih.gov/pubmed/29374410
http://dx.doi.org/10.22034/APJCP.2018.19.1.253
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