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Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth

Basal cell carcinoma (BCC) commonly affects the elderly and is mostly confined to the head and neck region. Only 10% of all cases occur on the trunk. We presented a case of bullous lesion on the abdomen in a young male, initially diagnosed by clinicians as a vascular nevus. Histopathological examina...

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Autores principales: Tyagi, Ruchita, Kaur, Dilpreet, Kaur, Gursheen, Garg, Bhavna, Sood, Neena, Gupta, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844689/
https://www.ncbi.nlm.nih.gov/pubmed/29563940
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author Tyagi, Ruchita
Kaur, Dilpreet
Kaur, Gursheen
Garg, Bhavna
Sood, Neena
Gupta, Sunil
author_facet Tyagi, Ruchita
Kaur, Dilpreet
Kaur, Gursheen
Garg, Bhavna
Sood, Neena
Gupta, Sunil
author_sort Tyagi, Ruchita
collection PubMed
description Basal cell carcinoma (BCC) commonly affects the elderly and is mostly confined to the head and neck region. Only 10% of all cases occur on the trunk. We presented a case of bullous lesion on the abdomen in a young male, initially diagnosed by clinicians as a vascular nevus. Histopathological examination and immunohistochemistry (IHC) revealed it to be Nodular cystic variant of BCC. This rare variant of BCC morphologically resembles benign skin adnexal tumor of Eccrine syringofibroadenoma. Ber Ep4 positivity on IHC established the correct diagnosis. This case highlights that nodular cystic variant of BCC can be a diagnostic dilemma for clinicians and pathologists.
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spelling pubmed-58446892018-03-21 Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth Tyagi, Ruchita Kaur, Dilpreet Kaur, Gursheen Garg, Bhavna Sood, Neena Gupta, Sunil Iran J Pathol Case Report Basal cell carcinoma (BCC) commonly affects the elderly and is mostly confined to the head and neck region. Only 10% of all cases occur on the trunk. We presented a case of bullous lesion on the abdomen in a young male, initially diagnosed by clinicians as a vascular nevus. Histopathological examination and immunohistochemistry (IHC) revealed it to be Nodular cystic variant of BCC. This rare variant of BCC morphologically resembles benign skin adnexal tumor of Eccrine syringofibroadenoma. Ber Ep4 positivity on IHC established the correct diagnosis. This case highlights that nodular cystic variant of BCC can be a diagnostic dilemma for clinicians and pathologists. Iranian Society of Pathology 2017 2017-10-01 /pmc/articles/PMC5844689/ /pubmed/29563940 Text en © 2017, IRANIAN JOURNAL OF PATHOLOGY. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tyagi, Ruchita
Kaur, Dilpreet
Kaur, Gursheen
Garg, Bhavna
Sood, Neena
Gupta, Sunil
Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth
title Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth
title_full Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth
title_fullStr Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth
title_full_unstemmed Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth
title_short Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth
title_sort nodular cystic basal cell carcinoma of the trunk: a diagnostic dilemma in an unsuspecting youth
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844689/
https://www.ncbi.nlm.nih.gov/pubmed/29563940
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