The transcription factors Runx3 and ThPOK cross-regulate acquisition of cytotoxic function by human Th1 lymphocytes

Cytotoxic CD4 (CD4(CTX)) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their development remains poorly understood. In the context of human cytomegalovirus infection, a significant proportion of CD4 T cells displays cytotoxic functions...

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Detalles Bibliográficos
Autores principales: Serroukh, Yasmina, Gu-Trantien, Chunyan, Hooshiar Kashani, Baharak, Defrance, Matthieu, Vu Manh, Thien-Phong, Azouz, Abdulkader, Detavernier, Aurélie, Hoyois, Alice, Das, Jishnu, Bizet, Martin, Pollet, Emeline, Tabbuso, Tressy, Calonne, Emilie, van Gisbergen, Klaas, Dalod, Marc, Fuks, François, Goriely, Stanislas, Marchant, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844691/
https://www.ncbi.nlm.nih.gov/pubmed/29488879
http://dx.doi.org/10.7554/eLife.30496

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