Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wing

Cell fate determination during development often requires morphogen transport from producing to distant responding cells. Hedgehog (Hh) morphogens present a challenge to this concept, as all Hhs are synthesized as terminally lipidated molecules that form insoluble clusters at the surface of producin...

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Detalles Bibliográficos
Autores principales: Schürmann, Sabine, Steffes, Georg, Manikowski, Dominique, Kastl, Philipp, Malkus, Ursula, Bandari, Shyam, Ohlig, Stefanie, Ortmann, Corinna, Rebollido-Rios, Rocio, Otto, Mandy, Nüsse, Harald, Hoffmann, Daniel, Klämbt, Christian, Galic, Milos, Klingauf, Jürgen, Grobe, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844694/
https://www.ncbi.nlm.nih.gov/pubmed/29522397
http://dx.doi.org/10.7554/eLife.33033

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