Targeting pediatric sarcoma with a bispecific ligand immunotoxin targeting urokinase and epidermal growth factor receptors

Children with high risk sarcoma have a poor prognosis despite surgical resection, irradiation and chemotherapy. Alternative therapies are urgently needed. Urokinase-type plasminogen activator receptor (uPAR) and epidermal growth factor receptor (EGFR) are surface proteins expressed by some pediatric...

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Detalles Bibliográficos
Autores principales: Pilbeam, Kristy, Wang, Hongbo, Taras, Elizabeth, Bergerson, Rachel J., Ettestad, Brianna, DeFor, Todd, Borgatti, Antonella, Vallera, Daniel A., Verneris, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844719/
https://www.ncbi.nlm.nih.gov/pubmed/29552283
http://dx.doi.org/10.18632/oncotarget.21187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844719/
https://www.ncbi.nlm.nih.gov/pubmed/29552283
http://dx.doi.org/10.18632/oncotarget.21187

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