The role of exosomal non-coding RNAs in cancer metastasis

An increasing number of studies has confirmed that many cells can secrete vesicles or exosomes in eukaryotes, which contain important nucleic acids, proteins and lipids and play important roles in cell communication and tumor metastasis. This paper summarizes the comprehensive function of exosomal n...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jin-Peng, Tang, Yan-Yan, Fan, Chun-Mei, Guo, Can, Zhou, Yan-Hong, Li, Zheng, Li, Xiao-Ling, Li, Yong, Li, Gui-Yuan, Xiong, Wei, Zeng, Zhao-Yang, Xiong, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844764/
https://www.ncbi.nlm.nih.gov/pubmed/29552328
http://dx.doi.org/10.18632/oncotarget.23552
_version_ 1783305301360902144
author Wang, Jin-Peng
Tang, Yan-Yan
Fan, Chun-Mei
Guo, Can
Zhou, Yan-Hong
Li, Zheng
Li, Xiao-Ling
Li, Yong
Li, Gui-Yuan
Xiong, Wei
Zeng, Zhao-Yang
Xiong, Fang
author_facet Wang, Jin-Peng
Tang, Yan-Yan
Fan, Chun-Mei
Guo, Can
Zhou, Yan-Hong
Li, Zheng
Li, Xiao-Ling
Li, Yong
Li, Gui-Yuan
Xiong, Wei
Zeng, Zhao-Yang
Xiong, Fang
author_sort Wang, Jin-Peng
collection PubMed
description An increasing number of studies has confirmed that many cells can secrete vesicles or exosomes in eukaryotes, which contain important nucleic acids, proteins and lipids and play important roles in cell communication and tumor metastasis. This paper summarizes the comprehensive function of exosomal non-coding RNAs. Although some studies have shown that exosomes mediate tumor signal transduction, the functional mechanism of the tumor metastasis remains to be elucidated. In this paper, we reviewed the role of exosomal non-coding RNAs in mediating cancer metastasis in the tumor microenvironment to provide new ideas for the study of tumor pathophysiology.
format Online
Article
Text
id pubmed-5844764
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-58447642018-03-16 The role of exosomal non-coding RNAs in cancer metastasis Wang, Jin-Peng Tang, Yan-Yan Fan, Chun-Mei Guo, Can Zhou, Yan-Hong Li, Zheng Li, Xiao-Ling Li, Yong Li, Gui-Yuan Xiong, Wei Zeng, Zhao-Yang Xiong, Fang Oncotarget Review An increasing number of studies has confirmed that many cells can secrete vesicles or exosomes in eukaryotes, which contain important nucleic acids, proteins and lipids and play important roles in cell communication and tumor metastasis. This paper summarizes the comprehensive function of exosomal non-coding RNAs. Although some studies have shown that exosomes mediate tumor signal transduction, the functional mechanism of the tumor metastasis remains to be elucidated. In this paper, we reviewed the role of exosomal non-coding RNAs in mediating cancer metastasis in the tumor microenvironment to provide new ideas for the study of tumor pathophysiology. Impact Journals LLC 2017-12-21 /pmc/articles/PMC5844764/ /pubmed/29552328 http://dx.doi.org/10.18632/oncotarget.23552 Text en Copyright: © 2018 Wang et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review
Wang, Jin-Peng
Tang, Yan-Yan
Fan, Chun-Mei
Guo, Can
Zhou, Yan-Hong
Li, Zheng
Li, Xiao-Ling
Li, Yong
Li, Gui-Yuan
Xiong, Wei
Zeng, Zhao-Yang
Xiong, Fang
The role of exosomal non-coding RNAs in cancer metastasis
title The role of exosomal non-coding RNAs in cancer metastasis
title_full The role of exosomal non-coding RNAs in cancer metastasis
title_fullStr The role of exosomal non-coding RNAs in cancer metastasis
title_full_unstemmed The role of exosomal non-coding RNAs in cancer metastasis
title_short The role of exosomal non-coding RNAs in cancer metastasis
title_sort role of exosomal non-coding rnas in cancer metastasis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844764/
https://www.ncbi.nlm.nih.gov/pubmed/29552328
http://dx.doi.org/10.18632/oncotarget.23552
work_keys_str_mv AT wangjinpeng theroleofexosomalnoncodingrnasincancermetastasis
AT tangyanyan theroleofexosomalnoncodingrnasincancermetastasis
AT fanchunmei theroleofexosomalnoncodingrnasincancermetastasis
AT guocan theroleofexosomalnoncodingrnasincancermetastasis
AT zhouyanhong theroleofexosomalnoncodingrnasincancermetastasis
AT lizheng theroleofexosomalnoncodingrnasincancermetastasis
AT lixiaoling theroleofexosomalnoncodingrnasincancermetastasis
AT liyong theroleofexosomalnoncodingrnasincancermetastasis
AT liguiyuan theroleofexosomalnoncodingrnasincancermetastasis
AT xiongwei theroleofexosomalnoncodingrnasincancermetastasis
AT zengzhaoyang theroleofexosomalnoncodingrnasincancermetastasis
AT xiongfang theroleofexosomalnoncodingrnasincancermetastasis
AT wangjinpeng roleofexosomalnoncodingrnasincancermetastasis
AT tangyanyan roleofexosomalnoncodingrnasincancermetastasis
AT fanchunmei roleofexosomalnoncodingrnasincancermetastasis
AT guocan roleofexosomalnoncodingrnasincancermetastasis
AT zhouyanhong roleofexosomalnoncodingrnasincancermetastasis
AT lizheng roleofexosomalnoncodingrnasincancermetastasis
AT lixiaoling roleofexosomalnoncodingrnasincancermetastasis
AT liyong roleofexosomalnoncodingrnasincancermetastasis
AT liguiyuan roleofexosomalnoncodingrnasincancermetastasis
AT xiongwei roleofexosomalnoncodingrnasincancermetastasis
AT zengzhaoyang roleofexosomalnoncodingrnasincancermetastasis
AT xiongfang roleofexosomalnoncodingrnasincancermetastasis

Ejemplares similares