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Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells

The B cell antigen receptor (BCR) employs enzymatically inactive adaptor proteins to facilitate activation of intracellular signaling pathways. In animal model systems, adaptor proteins of the growth factor receptor-bound 2 (Grb2) family have been shown to serve critical functions in lymphocytes. Ho...

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Detalles Bibliográficos
Autores principales:	Vanshylla, Kanika, Bartsch, Caren, Hitzing, Christoffer, Krümpelmann, Laura, Wienands, Jürgen, Engels, Niklas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844867/ https://www.ncbi.nlm.nih.gov/pubmed/29523808 http://dx.doi.org/10.1038/s41598-018-22544-x

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