Cargando…

Increased intracellular activity of MP1102 and NZ2114 against Staphylococcus aureus in vitro and in vivo

Treatment of Staphylococcus aureus infections remains very difficult due to its capacity to survive intracellularly and its multidrug resistance. In this study, the extracellular/intracellular activities of plectasin derivatives-MP1102/NZ2114 were investigated against three methicillin-susceptible/-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiao, Wang, Xiumin, Teng, Da, Mao, Ruoyu, Hao, Ya, Yang, Na, Li, Zhanzhan, Wang, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844868/ https://www.ncbi.nlm.nih.gov/pubmed/29523806 http://dx.doi.org/10.1038/s41598-018-22245-5

Ejemplares similares

Optimization of expression conditions for a novel NZ2114-derived antimicrobial peptide-MP1102 under the control of the GAP promoter in Pichia pastoris X-33
por: Mao, Ruoyu, et al.
Publicado: (2015)

Design and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus
por: Chen, Huixian, et al.
Publicado: (2017)

In vitro and in vivo antibacterial effect of NZ2114 against Streptococcus suis type 2 infection in mice peritonitis models
por: Jiao, Jian, et al.
Publicado: (2017)

In vitro/vivo Mechanism of Action of MP1102 With Low/Nonresistance Against Streptococcus suis Type 2 Strain CVCC 3928
por: Zhao, Fei, et al.
Publicado: (2019)

Effect of NZ2114 against Streptococcus dysgalactiae biofilms and its application in murine mastitis model
por: Yang, Na, et al.
Publicado: (2022)

Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis
por: Yang, Na, et al.
Publicado: (2017)

Killing of Staphylococcus aureus and Salmonella enteritidis and neutralization of lipopolysaccharide by 17-residue bovine lactoferricins: improved activity of Trp/Ala-containing molecules
por: Hao, Ya, et al.
Publicado: (2017)

An Enhanced Variant Designed From DLP4 Cationic Peptide Against Staphylococcus aureus CVCC 546
por: Li, Bing, et al.
Publicado: (2020)

Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus
por: Li, Zhanzhan, et al.
Publicado: (2017)

Internalization, distribution, and activity of peptide H2 against the intracellular multidrug-resistant bovine mastitis-causing bacterium Staphylococcus aureus
por: Wang, Xiao, et al.
Publicado: (2019)

Therapeutic potential of a designed CSαβ peptide ID13 in Staphylococcus aureus-induced endometritis of mice
por: Li, Bing, et al.
Publicado: (2020)

Pharmacokinetics and Pharmacodynamics of Fungal Defensin NZX Against Staphylococcus aureus-Induced Mouse Peritonitis Model
por: Zheng, Xueling, et al.
Publicado: (2022)

Marine Peptide-N6NH2 and Its Derivative-GUON6NH2 Have Potent Antimicrobial Activity Against Intracellular Edwardsiella tarda in vitro and in vivo
por: Han, Huihui, et al.
Publicado: (2021)

Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli
por: Wang, Zhenlong, et al.
Publicado: (2020)

C-terminal mini-PEGylation of a marine peptide N6 had potent antibacterial and anti-inflammatory properties against Escherichia coli and Salmonella strains in vitro and in vivo
por: Li, Ting, et al.
Publicado: (2022)

Design and Pharmacodynamics of Recombinant Fungus Defensin NZL with Improved Activity against Staphylococcus hyicus In Vitro and In Vivo
por: Liu, He, et al.
Publicado: (2021)

The Pharmacodynamics Study of Insect Defensin DLP4 Against Toxigenic Staphylococcus hyicus ACCC 61734 in Vitro and Vivo
por: Ma, Xuanxuan, et al.
Publicado: (2021)

Combined Systems Approaches Reveal a Multistage Mode of Action of a Marine Antimicrobial Peptide against Pathogenic Escherichia coli and Its Protective Effect against Bacterial Peritonitis and Endotoxemia
por: Wang, Xiumin, et al.
Publicado: (2016)

A cleavable chimeric peptide with targeting and killing domains enhances LPS neutralization and antibacterial properties against multi-drug resistant E. coli
por: Wang, Zhenlong, et al.
Publicado: (2023)

2114: The role of estrogen receptor-β in the development of the early endometriotic lesion
por: Knudtson, Jennifer, et al.
Publicado: (2018)

1102. Evaluation of Vancomycin Accumulation in Patients with Obesity
por: Assadoon, Maha, et al.
Publicado: (2021)

Mode of action of plectasin-derived peptides against gas gangrene-associated Clostridium perfringens type A
por: Zheng, Xueling, et al.
Publicado: (2017)

Therapy of intracellular Staphylococcus aureus by tigecyclin
por: Kreis, Carolin A, et al.
Publicado: (2013)

Improved Stability and Activity of a Marine Peptide-N6NH2 against Edwardsiella tarda and Its Preliminary Application in Fish
por: Han, Huihui, et al.
Publicado: (2020)

Dual Antibacterial Activities and Biofilm Eradication of a Marine Peptide-N6NH(2) and Its Analogs against Multidrug-Resistant Aeromonas veronii
por: Li, Ting, et al.
Publicado: (2020)

Recombinant of the Staphylococcal Bacteriophage Lysin CHAP(k) and Its Elimination against Streptococcus agalactiae Biofilms
por: Shan, Yuxue, et al.
Publicado: (2020)

The costs and benefits of water fluoridation in NZ
por: Moore, David, et al.
Publicado: (2017)

Codeine-containing medicines to be reclassified in NZ
Publicado: (2020)

Intracellular staphylococcus aureus: Live-in and let die
por: Fraunholz, Martin, et al.
Publicado: (2012)

Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly
por: Krauss, Jennifer L., et al.
Publicado: (2019)

Escherichia coli outer membrane protein F (OmpF): an immunogenic protein induces cross-reactive antibodies against Escherichia coli and Shigella
por: Wang, Xiao, et al.
Publicado: (2017)

PReS-FINAL-2114: The leptin and adiponectin as biomarkers of atherosclerosis in juvenile rheumatic arthritis
por: Opoka-Winiarska, V, et al.
Publicado: (2013)

Bi-fluorescent Staphylococcus aureus infection enables single-cell analysis of intracellular killing in vivo
por: Hinman, Kristina D., et al.
Publicado: (2023)

Development of Stabilimax NZ From Biomechanical Principles
por: Panjabi, Manohar M., et al.
Publicado: (2007)

NZ ACL Registry 2016 Annual Report
por: Love, Hamish
Publicado: (2017)

Intracellular Staphylococcus aureus persisters upon antibiotic exposure
por: Peyrusson, Frédéric, et al.
Publicado: (2020)

2114. Correlation Between Antifungal Consumption and the Distribution of Candida Species in a Hospital in Colombia
por: Arboleda, Harold T, et al.
Publicado: (2019)

OA11.02. A model of integrative care for low back pain
por: Eisenberg, D, et al.
Publicado: (2012)

1102. Ertapenem vs. Nonertapenem Antibiotics in Colorectal Surgery: A Stewardship Opportunity
por: LaDow, Tiffany, et al.
Publicado: (2019)

Roadmap for an imaging and modelling paediatric study in rural NZ
por: Kumar, Haribalan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4nlh3t9vt8ngcg9ni2v1lusidt