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Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism

Cisplatin is commonly utilized in the treatment of solid tumors. Its mechanism of action is complex and multiple mechanisms of resistance have been described. We sought to determine the impact of cisplatin-generated oxidative stress on head and neck squamous cell carcinoma (HNSCC) proliferation, sur...

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Detalles Bibliográficos
Autores principales:	Yu, Wangie, Chen, Yunyun, Dubrulle, Julien, Stossi, Fabio, Putluri, Vasanta, Sreekumar, Arun, Putluri, Nagireddy, Baluya, Dodge, Lai, Stephen Y., Sandulache, Vlad C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844883/ https://www.ncbi.nlm.nih.gov/pubmed/29523854 http://dx.doi.org/10.1038/s41598-018-22640-y

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