Allele-specific expression in a family quartet with autism reveals mono-to-biallelic switch and novel transcriptional processes of autism susceptibility genes

Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder, and the exact causal mechanism is unknown. Dysregulated allele-specific expression (ASE) has been identified in persons with ASD; however, a comprehensive analysis of ASE has not been conducted in a family quartet with...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Yen, Chang, Kai-Wei, Lin, Chia-Yi, Wu, Jia-Ying, Coon, Hilary, Huang, Pei-Hsin, Ho, Hong-Nerng, Akbarian, Schahram, Gau, Susan Shur-Fen, Huang, Hsien-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844893/
https://www.ncbi.nlm.nih.gov/pubmed/29523860
http://dx.doi.org/10.1038/s41598-018-22753-4

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