Tet Enzymes, Variants, and Differential Effects on Function

Discovery of the ten-eleven translocation 1 (TET) methylcytosine dioxygenase family of enzymes, nearly 10 years ago, heralded a major breakthrough in understanding the epigenetic modifications of DNA. Initially described as catalyzing the oxidation of methyl cytosine (5mC) to hydroxymethyl cytosine...

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Detalles Bibliográficos
Autores principales: Melamed, Philippa, Yosefzon, Yahav, David, Cfir, Tsukerman, Anna, Pnueli, Lilach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844914/
https://www.ncbi.nlm.nih.gov/pubmed/29556496
http://dx.doi.org/10.3389/fcell.2018.00022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844914/
https://www.ncbi.nlm.nih.gov/pubmed/29556496
http://dx.doi.org/10.3389/fcell.2018.00022

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