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Tet Enzymes, Variants, and Differential Effects on Function
Discovery of the ten-eleven translocation 1 (TET) methylcytosine dioxygenase family of enzymes, nearly 10 years ago, heralded a major breakthrough in understanding the epigenetic modifications of DNA. Initially described as catalyzing the oxidation of methyl cytosine (5mC) to hydroxymethyl cytosine...
Autores principales: | Melamed, Philippa, Yosefzon, Yahav, David, Cfir, Tsukerman, Anna, Pnueli, Lilach |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844914/ https://www.ncbi.nlm.nih.gov/pubmed/29556496 http://dx.doi.org/10.3389/fcell.2018.00022 |
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