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Muscle stem cell dysfunction impairs muscle regeneration in a mouse model of Down syndrome

Down syndrome, caused by trisomy 21, is characterized by a variety of medical conditions including intellectual impairments, cardiovascular defects, blood cell disorders and pre-mature aging phenotypes. Several somatic stem cell populations are dysfunctional in Down syndrome and their deficiencies m...

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Detalles Bibliográficos
Autores principales: Pawlikowski, Bradley, Betta, Nicole Dalla, Elston, Tiffany, Williams, Darian A., Olwin, Bradley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844921/
https://www.ncbi.nlm.nih.gov/pubmed/29523805
http://dx.doi.org/10.1038/s41598-018-22342-5