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Polyunsaturated Fatty Acid Biosynthesis Involving Δ8 Desaturation and Differential DNA Methylation of FADS2 Regulates Proliferation of Human Peripheral Blood Mononuclear Cells
Polyunsaturated fatty acids (PUFAs) are important for immune function. Limited evidence indicates that immune cell activation involves endogenous PUFA synthesis, but this has not been characterised. To address this, we measured metabolism of 18:3n-3 in quiescent and activated peripheral blood mononu...
Autores principales: | Sibbons, Charlene M., Irvine, Nicola A., Pérez-Mojica, J. Eduardo, Calder, Philip C., Lillycrop, Karen A., Fielding, Barbara A., Burdge, Graham C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844933/ https://www.ncbi.nlm.nih.gov/pubmed/29556240 http://dx.doi.org/10.3389/fimmu.2018.00432 |
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