Cargando…

Ultra-Sensitive HIV-1 Latency Viral Outgrowth Assays Using Humanized Mice

In the current quest for a complete cure for HIV/AIDS, highly sensitive HIV-1 latency detection methods are critical to verify full viral eradication. Until now, the in vitro quantitative viral outgrowth assays (qVOA) have been the gold standard for assessing latent HIV-1 viral burden. However, thes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmitt, Kimberly, Akkina, Ramesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844934/ https://www.ncbi.nlm.nih.gov/pubmed/29556230 http://dx.doi.org/10.3389/fimmu.2018.00344

Ejemplares similares

Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay
por: Stuelke, Erin L., et al.
Publicado: (2020)

Zika virus induced microcephaly and aberrant hematopoietic cell differentiation modeled in novel neonatal humanized mice
por: Schmitt, Kimberly, et al.
Publicado: (2023)

The mouse viral outgrowth assay: avatars for the detection of HIV-1 reservoirs
por: Metcalf Pate, Kelly A., et al.
Publicado: (2017)

Editorial: Development of Humanized Mouse Models for Infectious Diseases and Cancer
por: Tsuji, Moriya, et al.
Publicado: (2020)

Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay
por: Laird, Gregory M., et al.
Publicado: (2013)

Quantitation of the latent HIV-1 reservoir from the sequence diversity in viral outgrowth assays
por: Poon, Art F. Y., et al.
Publicado: (2018)

Gene Therapy Strategies for HIV/AIDS: Preclinical Modeling in Humanized Mice
por: Bennett, Michael S., et al.
Publicado: (2013)

A CD3/CD28 microbead-based HIV-1 viral outgrowth assay
por: Kuzmichev, Yury V, et al.
Publicado: (2017)

Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice
por: Schmitt, Kimberly, et al.
Publicado: (2020)

HIV-1 infection and CD4 T cell depletion in humanized Rag2-/-yc-/- mice
por: Berges, Bradford, et al.
Publicado: (2006)

Human Immunodeficiency Virus (HIV)-1 Integration Sites in Viral Latency
por: Rezaei, Simin D., et al.
Publicado: (2015)

A highly reproducible quantitative viral outgrowth assay for the measurement of the replication-competent latent HIV-1 reservoir
por: Fun, Axel, et al.
Publicado: (2017)

Human Immunodeficiency Virus 1 (HIV-1): Viral Latency, the Reservoir, and the Cure
por: Ventura, John D.
Publicado: (2020)

COVID-19 and SARS Coronavirus 2: Antibodies for the Immediate Rescue and Recovery Phase
por: Halstead, Scott B., et al.
Publicado: (2020)

The Effect of JAK1/2 Inhibitors on HIV Reservoir Using Primary Lymphoid Cell Model of HIV Latency
por: de Armas, Lesley R., et al.
Publicado: (2021)

Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice
por: Su, Hang, et al.
Publicado: (2019)

Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro
por: Olvera, Alex, et al.
Publicado: (2018)

HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency
por: Crespo, Raquel, et al.
Publicado: (2022)

Natural killer cells induce HIV-1 latency reversal after treatment with pan-caspase inhibitors
por: Furtado Milão, Joana, et al.
Publicado: (2022)

Diverse Impacts of HIV Latency-Reversing Agents on CD8+ T-Cell Function: Implications for HIV Cure
por: Clutton, Genevieve Tyndale, et al.
Publicado: (2018)

Human embryonic stem cell (hES) derived dendritic cells are functionally normal and are susceptible to HIV-1 infection
por: Bandi, Sriram, et al.
Publicado: (2008)

HIV-1 Latency and Viral Reservoirs: Existing Reversal Approaches and Potential Technologies, Targets, and Pathways Involved in HIV Latency Studies
por: Khanal, Sushant, et al.
Publicado: (2021)

HIV Latency-Reversing Agents Have Diverse Effects on Natural Killer Cell Function
por: Garrido, Carolina, et al.
Publicado: (2016)

Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth
por: Kiselinova, Maja, et al.
Publicado: (2016)

Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae-Evoked Pneumosepsis in Mice
por: Meijer, Mariska T., et al.
Publicado: (2021)

Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size
por: Stone, Mars, et al.
Publicado: (2020)

IRF7 expression correlates with HIV latency reversal upon specific blockade of immune activation
por: Ezeonwumelu, Ifeanyi Jude, et al.
Publicado: (2022)

Chemokines and Chemokine Receptors: Accomplices for Human Immunodeficiency Virus Infection and Latency
por: Wang, Zhuo, et al.
Publicado: (2017)

Long‐term evolutionary adaptation of SIVcpz toward HIV‐1 using a humanized mouse model
por: Schmitt, Kimberly, et al.
Publicado: (2022)

Humanized Rag1(−/−)γc(−/−) Mice Support Multilineage Hematopoiesis and Are Susceptible to HIV-1 Infection via Systemic and Vaginal Routes
por: Akkina, Ramesh, et al.
Publicado: (2011)

Metastatic Latency, a Veiled Threat
por: Kim, Kangsan, et al.
Publicado: (2019)

A Topical Microbicide Gel Formulation of CCR5 Antagonist Maraviroc Prevents HIV-1 Vaginal Transmission in Humanized RAG-hu Mice
por: Neff, C. Preston, et al.
Publicado: (2011)

Correction: Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth
por: Kiselinova, Maja, et al.
Publicado: (2016)

The Use of Ultra-Sensitive Molecular Assays in HIV Cure-Related Research
por: Kibirige, Catherine
Publicado: (2013)

Performance of an Ultra-Sensitive Assay Targeting the Circulating Anodic Antigen (CAA) for Detection of Schistosoma mansoni Infection in a Low Endemic Area in Brazil
por: Sousa, Mariana Silva, et al.
Publicado: (2019)

Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays
por: Kuzmichev, Yury V., et al.
Publicado: (2023)

HIV interactions with monocytes and dendritic cells: viral latency and reservoirs
por: Coleman, Christopher M, et al.
Publicado: (2009)

HIV‐1‐induced type I IFNs promote viral latency in macrophages
por: Dickey, Laura L., et al.
Publicado: (2022)

Humanized Mice for the Evaluation of Novel HIV-1 Therapies
por: Abeynaike, Shawn, et al.
Publicado: (2021)

Antigen Production After Latency Reversal and Expression of Inhibitory Receptors in CD8+ T Cells Limit the Killing of HIV-1 Reactivated Cells
por: Ruiz, Alba, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qm9pdtafcs4nju9a63904fngdl