Whole transcriptome profiling of Late-Onset Alzheimer’s Disease patients provides insights into the molecular changes involved in the disease

Alzheimer’s Disease (AD) is the most common cause of dementia affecting the elderly population worldwide. We have performed a comprehensive transcriptome profiling of Late-Onset AD (LOAD) patients using second generation sequencing technologies, identifying 2,064 genes, 47 lncRNAs and 4 miRNAs whose...

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Detalles Bibliográficos
Autores principales: Annese, Anita, Manzari, Caterina, Lionetti, Claudia, Picardi, Ernesto, Horner, David S., Chiara, Matteo, Caratozzolo, Mariano Francesco, Tullo, Apollonia, Fosso, Bruno, Pesole, Graziano, D’Erchia, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844946/
https://www.ncbi.nlm.nih.gov/pubmed/29523845
http://dx.doi.org/10.1038/s41598-018-22701-2

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