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Major pathologic response to alectinib in ALK-rearranged adenocarcinoma of the lung
BACKGROUND: Alectinib is a highly selective tyrosine kinase inhibitor of anaplastic lymphoma kinase (ALK) and provided a significantly prolonged progression-free survival compared with chemotherapy in patients with advanced non-small cell lung cancer (NSCLC) harboring rearrangements of the ALK gene....
Autores principales: | Imanishi, Naoko, Yoneda, Kazue, Taira, Akihiro, Ichiki, Yoshinobu, Sato, Naoko, Hisaoka, Masanori, Tanaka, Fumihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845085/ https://www.ncbi.nlm.nih.gov/pubmed/29524063 http://dx.doi.org/10.1186/s40792-018-0430-7 |
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