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Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice—an Aging Connection
While the refinement of existing and the development of new chemotherapeutic regimens has significantly improved cancer treatment outcomes and patient survival, chemotherapy still causes many persistent side effects. Central nervous system (CNS) toxicity is of particular concern, as cancer patients...
Autores principales: | Kovalchuk, Anna, Ilnytskyy, Yaroslav, Rodriguez-Juarez, Rocio, Katz, Amanda, Sidransky, David, Kolb, Bryan, Kovalchuk, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845109/ https://www.ncbi.nlm.nih.gov/pubmed/29556248 http://dx.doi.org/10.3389/fgene.2018.00058 |
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