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Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells
BACKGROUND: Intervertebral disc (IVD) degeneration is characterized by an early decrease in cellularity of the nucleus pulposus (NP) region, and associated extracellular matrix changes, reduced hydration, and progressive degeneration. Cell-based IVD therapy has emerged as an area of great interest,...
Autores principales: | Tang, Ruhang, Jing, Liufang, Willard, Vincent P., Wu, Chia-lung, Guilak, Farshid, Chen, Jun, Setton, Lori A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845143/ https://www.ncbi.nlm.nih.gov/pubmed/29523190 http://dx.doi.org/10.1186/s13287-018-0797-1 |
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