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Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells

BACKGROUND: Intervertebral disc (IVD) degeneration is characterized by an early decrease in cellularity of the nucleus pulposus (NP) region, and associated extracellular matrix changes, reduced hydration, and progressive degeneration. Cell-based IVD therapy has emerged as an area of great interest,...

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Detalles Bibliográficos
Autores principales: Tang, Ruhang, Jing, Liufang, Willard, Vincent P., Wu, Chia-lung, Guilak, Farshid, Chen, Jun, Setton, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845143/
https://www.ncbi.nlm.nih.gov/pubmed/29523190
http://dx.doi.org/10.1186/s13287-018-0797-1

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