Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes

BACKGROUND: Maternal malaria is a tropical scourge associated with poor pregnancy outcomes. Women become resistant to Plasmodium falciparum pregnancy malaria as they acquire antibodies to the variant surface antigen VAR2CSA, a leading vaccine candidate. Because malaria infection may increase VAR2CSA...

Descripción completa

Detalles Bibliográficos
Autores principales: Fried, Michal, Kurtis, Jonathan D., Swihart, Bruce, Morrison, Robert, Pond-Tor, Sunthorn, Barry, Amadou, Sidibe, Youssoufa, Keita, Sekouba, Mahamar, Almahamoudou, Andemel, Naissem, Attaher, Oumar, Dembele, Adama B., Cisse, Kadidia B., Diarra, Bacary S., Kanoute, Moussa B., Narum, David L., Dicko, Alassane, Duffy, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845157/
https://www.ncbi.nlm.nih.gov/pubmed/29523137
http://dx.doi.org/10.1186/s12936-018-2258-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845157/
https://www.ncbi.nlm.nih.gov/pubmed/29523137
http://dx.doi.org/10.1186/s12936-018-2258-9

Ejemplares similares