Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep

BACKGROUND: Sleep deprivation impairs learning, causes stress, and can lead to death. Notch and JNK-1 pathways impact C. elegans sleep in complex ways; these have been hypothesized to involve compensatory sleep. C. elegans DAF-16, a FoxO transcription factor, is required for homeostatic response to...

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Detalles Bibliográficos
Autores principales: Bennett, Heather L., Khoruzhik, Yulia, Hayden, Dustin, Huang, Huiyan, Sanders, Jarred, Walsh, Melissa B., Biron, David, Hart, Anne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845181/
https://www.ncbi.nlm.nih.gov/pubmed/29523076
http://dx.doi.org/10.1186/s12868-018-0408-1

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