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Effect of γ-secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis-like skin inflammation

BACKGROUND: Th17 cells and its effective cytokine IL-17A play an important role in the pathogenesis of abnormal immune responses in psoriasis. Notch1 signaling has been implicated in Th17 cell differentiation and function. In this study, our aim was to evaluate the possible inhibitory effect of Notc...

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Detalles Bibliográficos
Autores principales:	Ma, Lei, Xue, Haibo, Qi, Ruiqun, Wang, Yanqin, Yuan, Libing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845192/ https://www.ncbi.nlm.nih.gov/pubmed/29523162 http://dx.doi.org/10.1186/s12967-018-1442-6

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