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Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor β1

BACKGROUND: Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is the myofibroblast, and fibroblast t...

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Detalles Bibliográficos
Autores principales: Lawson, J. S., Syme, H. M., Wheeler-Jones, C. P. D., Elliott, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845201/
https://www.ncbi.nlm.nih.gov/pubmed/29523136
http://dx.doi.org/10.1186/s12917-018-1387-2