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Neuroprotective dobutamine treatment upregulates superoxide dismutase 3, anti-oxidant and survival genes and attenuates genes mediating inflammation

BACKGROUND: Labor subjects the fetus to an hypoxic episode and concomitant adrenomodullary catecholamine surge that may provide protection against the hypoxic insult. The beta1-adrenergic agonist dobutamine protects against hypoxia/aglycemia induced neuronal damage. We aimed to identify the associat...

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Detalles Bibliográficos
Autores principales: Markus, Tina, Ley, David, Hansson, Stefan R., Wieloch, Tadeusz, Ruscher, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845293/
https://www.ncbi.nlm.nih.gov/pubmed/29523072
http://dx.doi.org/10.1186/s12868-018-0415-2