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Pathologic and biochemical characterization of PrP(Sc) from elk with PRNP polymorphisms at codon 132 after experimental infection with the chronic wasting disease agent

BACKGROUND: The Rocky Mountain elk (Cervus elaphus nelsoni) prion protein gene (PRNP) is polymorphic at codon 132, with leucine (L132) and methionine (M132) allelic variants present in the population. In elk experimentally inoculated with the chronic wasting disease (CWD) agent, different incubation...

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Detalles Bibliográficos
Autores principales:	Moore, S. Jo, Vrentas, Catherine E., Hwang, Soyoun, West Greenlee, M. Heather, Nicholson, Eric M., Greenlee, Justin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845354/ https://www.ncbi.nlm.nih.gov/pubmed/29523205 http://dx.doi.org/10.1186/s12917-018-1400-9

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