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Melatonin Decreases Pulmonary Vascular Remodeling and Oxygen Sensitivity in Pulmonary Hypertensive Newborn Lambs

Background: Chronic hypoxia and oxidative stress during gestation lead to pulmonary hypertension of the neonate (PHN), a condition characterized by abnormal pulmonary arterial reactivity and remodeling. Melatonin has strong antioxidant properties and improves pulmonary vascular function. Here, we ai...

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Detalles Bibliográficos
Autores principales:	Astorga, Cristian R., González-Candia, Alejandro, Candia, Alejandro A., Figueroa, Esteban G., Cañas, Daniel, Ebensperger, Germán, Reyes, Roberto V., Llanos, Aníbal J., Herrera, Emilio A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845624/ https://www.ncbi.nlm.nih.gov/pubmed/29559926 http://dx.doi.org/10.3389/fphys.2018.00185

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