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In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri

Primary amebic meningoencephalitis (PAM) is a fatal infection caused by the free-living ameba Naegleria fowleri, popularly known as the “brain-eating ameba.” The drugs of choice in treating PAM are the antifungal amphotericin B and an antileishmanial miltefosine, but these are not FDA-approved for t...

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Detalles Bibliográficos
Autores principales: Debnath, Anjan, Nelson, Andrew T., Silva-Olivares, Angélica, Shibayama, Mineko, Siegel, Dionicio, McKerrow, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845744/
https://www.ncbi.nlm.nih.gov/pubmed/29559968
http://dx.doi.org/10.3389/fmicb.2018.00414