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Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies
Therapeutic molecules derived from antibodies have become a dominant class of drugs used to treat human disease. Increasingly, therapeutic antibodies are discovered using transgenic animal systems that have been engineered to express human antibodies. While the engineering details differ, these plat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845867/ https://www.ncbi.nlm.nih.gov/pubmed/29563917 http://dx.doi.org/10.3389/fimmu.2018.00460 |