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Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA). Neratinib blocks HER2 signaling and is effective in trastu...
Autores principales: | Wani, Tanveer A., Bakheit, Ahmed H., Abounassif, M. A., Zargar, Seema |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845959/ https://www.ncbi.nlm.nih.gov/pubmed/29564326 http://dx.doi.org/10.3389/fchem.2018.00047 |
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