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Indolylmaleimide Derivative IM-17 Shows Cardioprotective Effects in Ischemia-Reperfusion Injury
[Image: see text] We previously developed IM-54 as a novel type of inhibitor of hydrogen-peroxide-induced necrotic cell death. Here, we examined its cell death inhibition profile. IM-54 was found to selectively inhibit oxidative stress-induced necrosis, but it did not inhibit apoptosis induced by va...
Autores principales: | Dodo, Kosuke, Shimizu, Tadashi, Sasamori, Jun, Aihara, Kazuyuki, Terayama, Naoki, Nakao, Shuhei, Iuchi, Katsuya, Takahashi, Masahiro, Sodeoka, Mikiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846036/ https://www.ncbi.nlm.nih.gov/pubmed/29541357 http://dx.doi.org/10.1021/acsmedchemlett.7b00454 |
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