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Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel

BACKGROUND: Colorectal cancer (CRC) screening might be improved by using a measure of prior risk to modulate screening intensity or the faecal immunochemical test threshold. Intermediate molecular biomarkers could aid risk prediction by capturing both known and unknown risk factors. METHODS: We samp...

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Detalles Bibliográficos
Autores principales: Fernandez-Rozadilla, Ceres, Kartsonaki, Christiana, Woolley, Connor, McClellan, Michael, Whittington, Deb, Horgan, Gareth, Leedham, Simon, Kriaucionis, Skirmantas, East, James, Tomlinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846076/
https://www.ncbi.nlm.nih.gov/pubmed/29438375
http://dx.doi.org/10.1038/bjc.2017.486