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Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study
BACKGROUND: To evaluate and compare the effect of curcumin (CMN) mouth rinse with chlorhexidine (CHX) mouth rinse on clinical parameters and reactive oxygen metabolites (ROM) levels in participants with chronic gingivitis. MATERIALS AND METHODS: Thirty plaque-induced generalized chronic gingivitis p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846245/ https://www.ncbi.nlm.nih.gov/pubmed/29551867 http://dx.doi.org/10.4103/jisp.jisp_116_17 |
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author | Arunachalam, Lalitha Tanjore Sudhakar, Uma Vasanth, Johney Khumukchum, Sophia Selvam, Varsha Vardhini |
author_facet | Arunachalam, Lalitha Tanjore Sudhakar, Uma Vasanth, Johney Khumukchum, Sophia Selvam, Varsha Vardhini |
author_sort | Arunachalam, Lalitha Tanjore |
collection | PubMed |
description | BACKGROUND: To evaluate and compare the effect of curcumin (CMN) mouth rinse with chlorhexidine (CHX) mouth rinse on clinical parameters and reactive oxygen metabolites (ROM) levels in participants with chronic gingivitis. MATERIALS AND METHODS: Thirty plaque-induced generalized chronic gingivitis participants were randomly assigned to three groups – Group I (control/saline), Group II (CHX), and Group III (CMN), respectively. Baseline plaque index (PI), gingival index (GI), and salivary ROM were estimated, and oral prophylaxis was done. The parameters were recorded and evaluated again at the end of 4 weeks. RESULTS: Overall, the three groups have shown a significant reduction in PI, GI, and ROM levels at the end of 4 weeks. However, on intragroup comparison, only CMN group have shown significant reduction in ROM levels at the end of 4 weeks (P < 0.05). CONCLUSION: CMN mouth rinse can be considered as an alternative antigingivitis agent to CHX because of its anti-inflammatory and antioxidant properties. |
format | Online Article Text |
id | pubmed-5846245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-58462452018-03-16 Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study Arunachalam, Lalitha Tanjore Sudhakar, Uma Vasanth, Johney Khumukchum, Sophia Selvam, Varsha Vardhini J Indian Soc Periodontol Original Article BACKGROUND: To evaluate and compare the effect of curcumin (CMN) mouth rinse with chlorhexidine (CHX) mouth rinse on clinical parameters and reactive oxygen metabolites (ROM) levels in participants with chronic gingivitis. MATERIALS AND METHODS: Thirty plaque-induced generalized chronic gingivitis participants were randomly assigned to three groups – Group I (control/saline), Group II (CHX), and Group III (CMN), respectively. Baseline plaque index (PI), gingival index (GI), and salivary ROM were estimated, and oral prophylaxis was done. The parameters were recorded and evaluated again at the end of 4 weeks. RESULTS: Overall, the three groups have shown a significant reduction in PI, GI, and ROM levels at the end of 4 weeks. However, on intragroup comparison, only CMN group have shown significant reduction in ROM levels at the end of 4 weeks (P < 0.05). CONCLUSION: CMN mouth rinse can be considered as an alternative antigingivitis agent to CHX because of its anti-inflammatory and antioxidant properties. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5846245/ /pubmed/29551867 http://dx.doi.org/10.4103/jisp.jisp_116_17 Text en Copyright: © 2018 Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Arunachalam, Lalitha Tanjore Sudhakar, Uma Vasanth, Johney Khumukchum, Sophia Selvam, Varsha Vardhini Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study |
title | Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study |
title_full | Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study |
title_fullStr | Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study |
title_full_unstemmed | Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study |
title_short | Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study |
title_sort | comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: a clinical and biochemical study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846245/ https://www.ncbi.nlm.nih.gov/pubmed/29551867 http://dx.doi.org/10.4103/jisp.jisp_116_17 |
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