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Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens

OBJECTIVES: The aim is to identify the etiology of community acquired pneumonia in children with special reference to atypical bacteria and viruses. MATERIALS AND METHODS: A total of 94 pneumonia children were enrolled in the study. Sixty-seven did not have an etiological diagnosis by conventional c...

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Autores principales: Kumar, K Jagadish, Ashok Chowdary, KV, Usha, HC, Kulkarni, Maduri, Manjunath, VG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846259/
https://www.ncbi.nlm.nih.gov/pubmed/29487245
http://dx.doi.org/10.4103/lungindia.lungindia_391_16
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author Kumar, K Jagadish
Ashok Chowdary, KV
Usha, HC
Kulkarni, Maduri
Manjunath, VG
author_facet Kumar, K Jagadish
Ashok Chowdary, KV
Usha, HC
Kulkarni, Maduri
Manjunath, VG
author_sort Kumar, K Jagadish
collection PubMed
description OBJECTIVES: The aim is to identify the etiology of community acquired pneumonia in children with special reference to atypical bacteria and viruses. MATERIALS AND METHODS: A total of 94 pneumonia children were enrolled in the study. Sixty-seven did not have an etiological diagnosis by conventional culture. These children were subjected to immunofluorescence assay by Pneumoslide IgM. RESULTS: Ninety-four children were evaluated for etiology by conventional culture. Twenty-seven of them had the bacteriological diagnosis. Rest 67 were further analyzed for causative organism using Pneumoslide immunofluorescence test. Among this group, 38 (56.7%) had etiological diagnosis. Atypical bacteria were identified in 23 cases, most common being Mycoplasma pneumoniae and which was more common between 5 months and 2 years of age. Viruses were identified in 19 cases, and the most common virus was Respiratory syncytial virus. Mixed pathogens were identified in five children., M. pneumoniae was the common offending agent. CONCLUSIONS: Atypical bacteria and viruses play an important role as etiological agents in pneumonia in children. Pneumoslide IgM is useful for rapid detection of atypical bacteria and viruses.
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spelling pubmed-58462592018-03-16 Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens Kumar, K Jagadish Ashok Chowdary, KV Usha, HC Kulkarni, Maduri Manjunath, VG Lung India Original Article OBJECTIVES: The aim is to identify the etiology of community acquired pneumonia in children with special reference to atypical bacteria and viruses. MATERIALS AND METHODS: A total of 94 pneumonia children were enrolled in the study. Sixty-seven did not have an etiological diagnosis by conventional culture. These children were subjected to immunofluorescence assay by Pneumoslide IgM. RESULTS: Ninety-four children were evaluated for etiology by conventional culture. Twenty-seven of them had the bacteriological diagnosis. Rest 67 were further analyzed for causative organism using Pneumoslide immunofluorescence test. Among this group, 38 (56.7%) had etiological diagnosis. Atypical bacteria were identified in 23 cases, most common being Mycoplasma pneumoniae and which was more common between 5 months and 2 years of age. Viruses were identified in 19 cases, and the most common virus was Respiratory syncytial virus. Mixed pathogens were identified in five children., M. pneumoniae was the common offending agent. CONCLUSIONS: Atypical bacteria and viruses play an important role as etiological agents in pneumonia in children. Pneumoslide IgM is useful for rapid detection of atypical bacteria and viruses. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5846259/ /pubmed/29487245 http://dx.doi.org/10.4103/lungindia.lungindia_391_16 Text en Copyright: © 2018 Indian Chest Society http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kumar, K Jagadish
Ashok Chowdary, KV
Usha, HC
Kulkarni, Maduri
Manjunath, VG
Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens
title Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens
title_full Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens
title_fullStr Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens
title_full_unstemmed Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens
title_short Etiology of community acquired pneumonia among children in India with special reference to atypical pathogens
title_sort etiology of community acquired pneumonia among children in india with special reference to atypical pathogens
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846259/
https://www.ncbi.nlm.nih.gov/pubmed/29487245
http://dx.doi.org/10.4103/lungindia.lungindia_391_16
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