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Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

BACKGROUND: Recent animal studies have shown that mitochondrial dysfunction initiates and accelerates renal injury in sepsis, but its role in sepsis remains unknown. Mitochondrial stress or dying cells can lead to fragmentation of the mitochondrial genome, which is considered a surrogate marker of m...

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Detalles Bibliográficos
Autores principales:	Hu, Qiongyuan, Ren, Jianan, Ren, Huajian, Wu, Jie, Wu, Xiuwen, Liu, Song, Wang, Gefei, Gu, Guosheng, Guo, Kun, Li, Jieshou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846356/ https://www.ncbi.nlm.nih.gov/pubmed/29682165 http://dx.doi.org/10.1155/2018/8074936

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