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Natural Products for the Management and Prevention of Breast Cancer
Among all types of cancer, breast cancer is one of the most challenging diseases, which is responsible for a large number of cancer related deaths. Hormonal therapy, surgery, chemotherapy, and radiotherapy have been used as treatment of breast cancer, for a very long time. Due to severe side effects...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846366/ https://www.ncbi.nlm.nih.gov/pubmed/29681985 http://dx.doi.org/10.1155/2018/8324696 |
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author | Mitra, Sarmistha Dash, Raju |
author_facet | Mitra, Sarmistha Dash, Raju |
author_sort | Mitra, Sarmistha |
collection | PubMed |
description | Among all types of cancer, breast cancer is one of the most challenging diseases, which is responsible for a large number of cancer related deaths. Hormonal therapy, surgery, chemotherapy, and radiotherapy have been used as treatment of breast cancer, for a very long time. Due to severe side effects and multidrug resistance, these treatment approaches become increasingly ineffective. However, adoption of complementary treatment approach can be a big solution for this situation, as it is evident that compounds derived from natural source have a great deal of anticancer activity. Natural compounds can fight against aggressiveness of breast cancer, inhibit cancerous cell proliferation, and modulate cancer related pathways. A large number of research works are now focusing on the natural and dietary compounds and trying to find out new and more effective treatment strategies for the breast cancer patients. In this review, we discussed some significant natural chemical compounds with their mechanisms of actions, which can be very effective against the breast cancer and can be more potent by their proper modifications and further clinical research. Future research focusing on the natural anti-breast-cancer agents can open a new horizon in breast cancer treatment, which will play a great role in enhancing the survival rate of breast cancer patients. |
format | Online Article Text |
id | pubmed-5846366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-58463662018-04-22 Natural Products for the Management and Prevention of Breast Cancer Mitra, Sarmistha Dash, Raju Evid Based Complement Alternat Med Review Article Among all types of cancer, breast cancer is one of the most challenging diseases, which is responsible for a large number of cancer related deaths. Hormonal therapy, surgery, chemotherapy, and radiotherapy have been used as treatment of breast cancer, for a very long time. Due to severe side effects and multidrug resistance, these treatment approaches become increasingly ineffective. However, adoption of complementary treatment approach can be a big solution for this situation, as it is evident that compounds derived from natural source have a great deal of anticancer activity. Natural compounds can fight against aggressiveness of breast cancer, inhibit cancerous cell proliferation, and modulate cancer related pathways. A large number of research works are now focusing on the natural and dietary compounds and trying to find out new and more effective treatment strategies for the breast cancer patients. In this review, we discussed some significant natural chemical compounds with their mechanisms of actions, which can be very effective against the breast cancer and can be more potent by their proper modifications and further clinical research. Future research focusing on the natural anti-breast-cancer agents can open a new horizon in breast cancer treatment, which will play a great role in enhancing the survival rate of breast cancer patients. Hindawi 2018-02-26 /pmc/articles/PMC5846366/ /pubmed/29681985 http://dx.doi.org/10.1155/2018/8324696 Text en Copyright © 2018 Sarmistha Mitra and Raju Dash. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Mitra, Sarmistha Dash, Raju Natural Products for the Management and Prevention of Breast Cancer |
title | Natural Products for the Management and Prevention of Breast Cancer |
title_full | Natural Products for the Management and Prevention of Breast Cancer |
title_fullStr | Natural Products for the Management and Prevention of Breast Cancer |
title_full_unstemmed | Natural Products for the Management and Prevention of Breast Cancer |
title_short | Natural Products for the Management and Prevention of Breast Cancer |
title_sort | natural products for the management and prevention of breast cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846366/ https://www.ncbi.nlm.nih.gov/pubmed/29681985 http://dx.doi.org/10.1155/2018/8324696 |
work_keys_str_mv | AT mitrasarmistha naturalproductsforthemanagementandpreventionofbreastcancer AT dashraju naturalproductsforthemanagementandpreventionofbreastcancer |