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Brain atrophy and disability worsening in primary progressive multiple sclerosis: insights from the INFORMS study

OBJECTIVE: To investigate the relationship between brain volume and disability worsening over ≥3 years in the natural history of primary progressive multiple sclerosis using data from the placebo group of the INFORMS trial (n = 487; clinicaltrials.gov NCT00731692). METHODS: Magnetic resonance imagin...

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Detalles Bibliográficos
Autores principales: Miller, David H., Lublin, Fred D., Sormani, Maria Pia, Kappos, Ludwig, Yaldizli, Özgür, Freedman, Mark S., Cree, Bruce A. C., Weiner, Howard L., Lubetzki, Catherine, Hartung, Hans‐Peter, Montalban, Xavier, Uitdehaag, Bernard M. J., MacManus, David G., Yousry, Tarek A., Gandini Wheeler‐Kingshott, Claudia A. M., Li, Bingbing, Putzki, Norman, Merschhemke, Martin, Häring, Dieter A., Wolinsky, Jerry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846448/
https://www.ncbi.nlm.nih.gov/pubmed/29560379
http://dx.doi.org/10.1002/acn3.534