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Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux
Oxidative stress activates macroautophagy/autophagy and contributes to atherogenesis via lipophagic flux, a form of lipid removal by autophagy. However, it is not known exactly how endogenous antioxidant enzymes are involved in lipophagic flux. Here, we demonstrate that the antioxidant PRDX1 (peroxi...
Autores principales: | Jeong, Se-Jin, Kim, Sinai, Park, Jong-Gil, Jung, In-hyuk, Lee, Mi-Ni, Jeon, Sejin, Kweon, Hyae Yon, Yu, Dae-Yeul, Lee, Sang-Hak, Jang, Yangsoo, Kang, Sang Won, Han, Ki-Hwan, Miller, Yury I., Park, Young Mi, Cheong, Cheolho, Choi, Jae-Hoon, Oh, Goo Taeg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846566/ https://www.ncbi.nlm.nih.gov/pubmed/28605287 http://dx.doi.org/10.1080/15548627.2017.1327942 |
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