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Stage-dependent changes of β2-adrenergic receptor signaling in right ventricular remodeling in monocrotaline-induced pulmonary arterial hypertension

Right ventricular (RV) remodeling coupled with extensive apoptosis in response to unrestrained biomechanical stress may lead to RV failure (RVF), which is the immediate cause of death in the majority of patients with pulmonary arterial hypertension (PAH). Overexpression of β(2)-adrenergic receptor (...

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Detalles Bibliográficos
Autores principales: Sun, Fengjiao, Lu, Zhiqiang, Zhang, Yidan, Geng, Shihan, Xu, Mengxi, Xu, Liman, Huang, Yingying, Zhuang, Pengwei, Zhang, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846663/
https://www.ncbi.nlm.nih.gov/pubmed/29393391
http://dx.doi.org/10.3892/ijmm.2018.3449