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A facile doxorubicin-dichloroacetate conjugate nanomedicine with high drug loading for safe drug delivery

BACKGROUND: Doxorubicin (DOX) is an effective chemotherapeutic agent but severe side effects limit its clinical application. Nanoformulations can reduce the toxicity while still have various limitations, such as complexity, low drug loading capability and excipient related concerns. METHODS: An amph...

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Detalles Bibliográficos
Autores principales:	Yang, Conglian, Wu, Tingting, Qin, Yuting, Qi, Yan, Sun, Yu, Kong, Miao, Jiang, Xue, Qin, Xianya, Shen, Yaqi, Zhang, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846746/ https://www.ncbi.nlm.nih.gov/pubmed/29563787 http://dx.doi.org/10.2147/IJN.S154361

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