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Inhibition of cell proliferation and migration through nucleobase-modified polyamidoamine-mediated p53 delivery

INTRODUCTION: The nucleobase 2-amino-6-chloropurine-modified polyamidoamine (AP-PAMAM) was used as a carrier for p53 gene delivery to achieve the antitumor effects. METHODS AND MATERIALS: The condensation of p53 plasmid was studied through gel retardation assay, and the transfection efficiency was e...

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Detalles Bibliográficos
Autores principales:	Han, Haobo, Chen, Wenqi, Yang, Jiebing, Liang, Xiao, Wang, Yudi, Li, Quanshun, Yang, Yan, Li, Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846749/ https://www.ncbi.nlm.nih.gov/pubmed/29563788 http://dx.doi.org/10.2147/IJN.S146917

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