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High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing
The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis—a low-resolution genome-wide chromosome analysis—is still the gold standard, it often needs to be complemented with other methods to increase resolution. To evalu...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846771/ https://www.ncbi.nlm.nih.gov/pubmed/29529047 http://dx.doi.org/10.1371/journal.pone.0193928 |