Triplet-Based Codon Organization Optimizes the Impact of Synonymous Mutation on Nucleic Acid Molecular Dynamics

Since the elucidation of the genetic code almost 50 years ago, many nonrandom aspects of its codon organization remain only partly resolved. Here, we investigate the recent hypothesis of ‘dual-use’ codons which proposes that in addition to allowing adjustment of codon optimization to tRNA abundance,...

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Detalles Bibliográficos
Autores principales: Babbitt, Gregory A., Coppola, Erin E., Mortensen, Jamie S., Ekeren, Patrick X., Viola, Cosmo, Goldblatt, Dallan, Hudson, André O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846835/
https://www.ncbi.nlm.nih.gov/pubmed/29344693
http://dx.doi.org/10.1007/s00239-018-9828-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846835/
https://www.ncbi.nlm.nih.gov/pubmed/29344693
http://dx.doi.org/10.1007/s00239-018-9828-x

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