CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function

Various kinases, including a cyclin-dependent kinase (CDK) family member, regulate the growth and functions of primary cilia, which perform essential roles in signaling and development. Neurological disorders linked to CDK-Like (CDKL) proteins suggest that these underexplored kinases may have simila...

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Detalles Bibliográficos
Autores principales: Canning, Peter, Park, Kwangjin, Gonçalves, João, Li, Chunmei, Howard, Conor J., Sharpe, Timothy D., Holt, Liam J., Pelletier, Laurence, Bullock, Alex N., Leroux, Michel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846859/
https://www.ncbi.nlm.nih.gov/pubmed/29420175
http://dx.doi.org/10.1016/j.celrep.2017.12.083

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