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The Convergence of Dopamine and α-Synuclein: Implications for Parkinson’s Disease
In Parkinson’s disease (PD), the loss of dopamine-producing neurons in the substantia nigra (SN) leads to severe motor impairment, and pathological inclusions known as Lewy bodies contain aggregated α-synuclein protein. The relationship of α-synuclein aggregation and dopaminergic degeneration is unc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846926/ https://www.ncbi.nlm.nih.gov/pubmed/29559809 http://dx.doi.org/10.1177/1179069518761360 |