Impact of multi-gene mutational profiling on clinical trial outcomes in metastatic breast cancer

PURPOSE: Next-generation sequencing (NGS) has identified recurrent genomic alterations in metastatic breast cancer (MBC); however, the clinical utility of incorporating routine sequencing to guide treatment decisions in this setting is unclear. We examine the frequency of genomic alterations in MBC...

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Detalles Bibliográficos
Autores principales: Pezo, Rossanna C., Chen, Tom W., Berman, Hal K., Mulligan, Anna M., Razak, Albiruni A., Siu, Lillian L., Cescon, David W., Amir, Eitan, Elser, Christine, Warr, David G., Sridhar, Srikala S., Yu, Celeste, Wang, Lisa, Stockley, Tracy L., Kamel-Reid, Suzanne, Bedard, Philippe L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847065/
https://www.ncbi.nlm.nih.gov/pubmed/29177603
http://dx.doi.org/10.1007/s10549-017-4580-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847065/
https://www.ncbi.nlm.nih.gov/pubmed/29177603
http://dx.doi.org/10.1007/s10549-017-4580-2

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