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Predictive accuracy of combined genetic and environmental risk scores
The substantial heritability of most complex diseases suggests that genetic data could provide useful risk prediction. To date the performance of genetic risk scores has fallen short of the potential implied by heritability, but this can be explained by insufficient sample sizes for estimating highl...
Autores principales: | Dudbridge, Frank, Pashayan, Nora, Yang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847122/ https://www.ncbi.nlm.nih.gov/pubmed/29178508 http://dx.doi.org/10.1002/gepi.22092 |
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