Ligand-induced perturbation of the HIF-2α:ARNT dimer dynamics

Hypoxia inducible factors (HIFs) are transcription factors belonging to the basic helix−loop−helix PER-ARNT-SIM (bHLH-PAS) protein family with a role in sensing oxygen levels in the cell. Under hypoxia, the HIF-α degradation pathway is blocked and dimerization with the aryl hydrocarbon receptor nucl...

Descripción completa

Detalles Bibliográficos
Autores principales: Motta, Stefano, Minici, Claudia, Corrada, Dario, Bonati, Laura, Pandini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847239/
https://www.ncbi.nlm.nih.gov/pubmed/29489822
http://dx.doi.org/10.1371/journal.pcbi.1006021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847239/
https://www.ncbi.nlm.nih.gov/pubmed/29489822
http://dx.doi.org/10.1371/journal.pcbi.1006021

Ejemplares similares