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The big CGRP flood - sources, sinks and signalling sites in the trigeminovascular system

BACKGROUND: Calcitonin gene-related peptide (CGRP) has long been a focus of migraine research, since it turned out that inhibition of CGRP or CGRP receptors by antagonists or monoclonal IgG antibodies was therapeutic in frequent and chronic migraine. This contribution deals with the questions, from...

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Detalles Bibliográficos
Autor principal: Messlinger, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847494/
https://www.ncbi.nlm.nih.gov/pubmed/29532195
http://dx.doi.org/10.1186/s10194-018-0848-0