TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Transcription-blocking DNA lesions are removed by transcription-coupled nucleotide excision repair (TC-NER) to preserve cell viability. TC-NER is triggered by the stalling of RNA polymerase II at DNA lesions, leading to the recruitment of TC-NER-specific factors such as the CSA–DDB1–CUL4A–RBX1 culli...

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Detalles Bibliográficos
Autores principales: Pines, Alex, Dijk, Madelon, Makowski, Matthew, Meulenbroek, Elisabeth M., Vrouwe, Mischa G., van der Weegen, Yana, Baltissen, Marijke, French, Pim J., van Royen, Martin E., Luijsterburg, Martijn S., Mullenders, Leon H., Vermeulen, Michiel, Vermeulen, Wim, Pannu, Navraj S., van Attikum, Haico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847541/
https://www.ncbi.nlm.nih.gov/pubmed/29531219
http://dx.doi.org/10.1038/s41467-018-03484-6

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